產(chǎn)品描述

Recombinant Human Ephrin Type-B Receptor 1 is produced by our Mammalian expression system and the target gene encoding Met18-Pro540 is expressed with a human IgG1 Fc tag at the C-terminus.
產(chǎn)品別稱
Ephrin Type-B Receptor 1;ELK;EPH Tyrosine Kinase 2;EPH-Like Kinase 6;EK6;hEK6;Neuronally-Expressed EPH;Related Tyrosine Kinase;NET;Tyrosine-Protein Kinase Receptor EPH-2;EPHB1;ELK;EPHT2;HEK6
分子量
85.6 KDa
表觀分子量
85-110 KDa, reducing conditions
劑型描述
Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
內(nèi)毒素
Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
復溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
保存條件
Lyophilized protein should be stored at ≤ -20℃, stable for one year after receipt.
Reconstituted protein solution can be stored at 2-8℃ for 2-7 days.
Aliquots of reconstituted samples are stable at ≤ -20℃ for 3 months.
運輸條件
The product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.
產(chǎn)品背景
Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile α motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to ephrin-B1, ephrin-B2 and ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.

RecombinantHumanEphB1(C-Fc)

RecombinantHumanEphB1(C-Fc)